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Cayman Chemical MR1 ImunoaFInIty Sorbent 400uL
An inhibitor of MKNK1 and MKNK2 (IC50s 0.064 and 0.086 UM respectively) selective for MKNK1 and MKNK2 over a panel of 104 kinases at 1 UM inhibits phosphorylation of eIF4E in HeLa cells (IC50 0.321 UM) enhances dasatinib-induced tumor growth inhibition in a K562 mouse xenograft model prevents weight gain in a mouse model of high-fat diet-induced obesity at 100 mg/kg
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